Designer Bodies – DNA Manipulation to Recreate Ourselves

Many people often wish that it was possible to recreate themselves to be ‘perfect,’ physically, mentally or both. To fulfil this desire, scientists are exploring how DNA manipulation can be used to change plants and animals, as well as redesign our human bodies and minds. DNA is the source code of all forms of life, and changes in our genetic composition may make it possible for us to survive longer, and in more extreme situations. Founding Director of the Life Sciences project at Harvard Business School, Juan Enriquez, has spoken about using gene editing to take evolution into our hands, instead of depending on nature to choose which species survive. One of the easiest ways to accomplish this is through CRISPR, a genome editing technique that can modify a specific part of a gene without harming any others.

Enriquez pointed out the evolution of science itself, which used to be about discovery but is now about creation.’ Technology has changed the pattern of our world from ‘survival of the fittest,’ to one in which humans can decide which species live and die. We can also modify the genes of plants and animals to live in conditions they would previously have been unable to survive in. Although the ability to modify the body of different species is phenomenal, an even greater achievement is the ability to recreate our minds.

DNA manipulation means humans can decide who they want to be, and which experience they want to dominate their lives at any given moment. The mind can be shaped by altering, creating and deleting memories, which are the foundation of who we are. This would allow people to change their entire identity, past experiences and personal beliefs almost instantaneously. This altering of self, with technology, raises many questions and the possibility of harmful or immoral consequences. Would justice still be served if a person had no recollection of committing a crime? Would other members of society be affected if somebody ‘created’ a relationship in their head? Would existing financial obligations be avoided by changing the circumstances in the mind?

Although the question of the morality remains, the ability to change our DNA would be frequently lifesaving. In addition to altering or removing DNA associated with genetic illnesses, the length of time taken to make vaccinations would decrease significantly. Future survival would be guaranteed, even in the event of a catastrophic planetary event, as DNA could be altered for life outside of our atmosphere. Space exploration would increase exponentially, as Enriquez believes that the human species was created for expansion. ‘As explorers at heart’ we will always be drawn to the unknown, breaking barriers, creating and recreating, with DNA manipulation being only a part of the process of expanding our beings.

Cancer Fighting Robots – Nanotechnology to Kill Tumors

The number of people that become affected with cancer has risen steadily for several decades. Throughout this time, scientists have been trying to find ways of killing tumors to prolong the lives of these individuals. Nanotechnology has already advanced the medical field significantly, as it is now used to help identify and treat disease. Researchers have been working on creating nanorobots with the ability to disintegrate cancerous tumors in the body, but many previous designs have been rejected because they harmed healthy tissues and cells surrounding the tumor. Recently, however, scientists have developed a nanorobot that can shrink cancerous cells by cutting off their blood supply, effectively ‘starving’ the tumor.

The study has been a collaboration between Arizona State University and National Centre for Nano Science and Technology of the Chinese Academy of Studies, and proves that nanorobots can effectively eliminate cancer tumors. The results were published in Nature Biotechnology, and included conclusive tests in which the blood supply to cancerous tumors in mice, had been cut off resulting in the tumors’ death. The tissue began to shrink two weeks after treatment, and the treatment effectively removed breast, ovarian, lung and other types of cancerous tumors.

The technique used to create the nanorobots is called DNA origami, derived from the Japanese art of paper folding. Scientists have found where it is possible to fold DNA to create different shapes, and modified the technique to be used on a single strand of DNA. Shorter strands of compatible DNA, called staples, and positioned along the strand causing it to fold upon itself at various intervals. The DNA cells are easily replicated in E. Coli, which makes it an accessible, cost effective and reliable source of providing the necessary raw materials. Each nanorobot is made from a flat DNA origami sheet 90 x 60 nanometers. This is 1000 times thinner than a human hair, and the system is the first capable of targeting the cancerous cells so precisely. The process’s efficiency is increased because of an enzyme that causes clots to form in the blood vessels feeding the tumor, being attached to the sheet.

Although still in its infancy stage, the results in the study with the mice have been promising and scientists are hoping to proceed to the next step. The treatment would need to be clinically tested before decisive results can be published. In addition to saving lives by destroying cancerous tumors, scientists believe that the same technique can be applied to other medical needs, such as delivering drugs to a targeted area. As testing continues, it is possible that the uses of the nanorobot will expand and it will become a widespread solution to other medical problems.

Rising Sea Levels – The Need for a Global Solution

Scientists have been monitoring the world’s sea levels for several decades, and have realized that the rate at which they are rising has significantly increased. The analysis of 25 years of satellite data shows that the height of most oceans will continue to rise by at least 4 inches each decade, if global changes aren’t implemented. This means that by the end of the century the sea levels will be over two feet above measurements taken in 2005. The 25 years of evidence was published in Proceedings of the National Academy of Science, and demonstrated in 3D.

Although these figures don’t seem that devastating at first glance, even a small increase in sea levels causes great destruction in coastal areas. As water comes further inland, it causes erosion, loss of habitat for aquatic and coastal animals and plants, flooding and soil contamination. Higher sea levels also mean that storms will cause more damage. Flooding is currently the leading cause of death by natural disaster. Hundreds of millions of people are now living in areas that are becoming increasing susceptible to flooding. As the sea levels continue to rise many of them will be forced to relocate, and low-lying islands may be completely submerged.

There are three primary factors, all resulting from global warming, which are contributing to the rising levels of the world’s major water bodies.

Thermal Expansion – As the Earth’s atmosphere gets hotter, the oceans’ water also increases in temperature and begins to expand. This causes the sea levels to rise as the water can only expand upwards.

Ice Loss from Greenland and West Antarctica – Increased heat on the planet is also causing the ice sheets that cover these regions to melt at a faster pace. Research has shown where meltwater from above, and seawater from below, is seeping in between the sheets, causing the ice streams to move more quickly into the sea. Higher sea temperatures also result in the ice shelves, extending from Antarctica, to melt.

Melting Glaciers and Polar Ice Caps – Each summer, large ice formations melt, and are normally replaced in winter by snow. This natural balance worked to maintain sea levels for centuries. The higher temperatures, caused by global warming, means that more ice has begun to melt each summer. In addition, winter is coming later each year, and spring starts earlier, meaning that there is significantly less snowfall to replace the amount lost each summer.

The rising sea levels are already affecting countries all over the world, including the United States. The US Geological Survey recently conducted a study which shows that without human intervention, a large percentage of Southern California beaches will become completely eroded. This will both threaten one of the state’s main sources of income, and make inland communities more susceptible to flooding. The overall study shows where a global effort needs to be made to control the rising sea levels, as soon as we possibly can.

Future Pandemic – Is an Outbreak Inevitable?

Scientists, and other researchers, spend much of their time developing ways to prevent possible disasters, both natural and unnatural, from taking place. History is famous for repeating itself, and there have been several recorded pandemics that were responsible for the deaths of a large percentage of the population. The Spanish Flu outbreak, in 1918, is one of the most deadly examples. An incredibly contagious form of influenza, this virus affected everybody and spread to some of the most remote parts of the planet. It is estimated that, over the course of two years, the Spanish Flu killed between 50-100 million people worldwide.

Although our medical techniques, and pharmaceuticals, have advanced significantly since the early 20th century; The General Director of the World Health Organization (WHO), Tedros Adhanom, has addressed the fact that we are still as unprepared for a pandemic as we were at the beginning of the 20th century. The dreaded event could begin in any country and spread quickly, before most nations were aware of its presence. Although this is a scenario we have witnessed many times in horror books, and films, the possibility of it happening in real life is much higher than most of us would like to admit.

Tedros pointed out that, ‘Universal health coverage is the greatest threat to global health.’ He went on to explain that as many as 3.5 billion people still do not have access to essential health services. Others that can attain the services are often forced into poverty, because of the high costs of this care. To avoid this problem many people neglect seeking medical treatment, even when it is necessary. This results in many illnesses progressing further than can be treated, and an unnecessary spreading of infectious diseases. This negligence could result in the earliest signs of an outbreak being overlooked.

Each country’s health organization relies on funding from their government to monitor the spread of diseases, as well as ensure the proper treatment. The (CDC) Centre for Disease Control and Prevention, in the United States, has recently announced that its budget for the epidemic prevention programs is being cut by 80%. In light of a possibly outbreak occurring at any moment, other countries are also experiencing the same difficulties. This demonstrates that governments are viewing healthcare as an unnecessary cost, instead of a necessary investment.

Tedros pointed out that healthy citizens are an advantage to the economy of any country. It has been proven that proper healthcare from children are in the womb, which is continued throughout their childhood, helps to make them stronger members of society. He also noted that at the moment a possible pandemic couldn’t be predicted, but dreads the terrible toll it would take on humanity. Despite there being no guarantee that a pandemic free world will ever be created, he is urging that we take back the control of our own lives. The best way to ensure our survival is by governments investing in proper healthcare, in every way possible, for each and every one of its citizens.

Printed Solar Tiles – Life Changing Clean Energy Technology

The size of traditional solar panels has made them difficult to move around, as well as relatively expensive and not conducive to life in many parts of the world. Researchers at The University of Newcastle, Australia, are hoping to change the way the sun’s energy is harvested with their printed solar tiles. Their method, called functional printing, is cheaper, easier and quicker than other solar panels, and an upgrade to the way the sun’s rays are converted to energy. Professor Paul Dastoor has led the team’s research, and they are now in their final testing phase monitoring Australia’s first printed solar field.

The technique uses an advanced electronic ink which is printed on paper thin, clear laminated sheets using a conventional printer. The ink is made by the team, from non-toxic carbon-based materials, which can be used as is or further processed into water-based inks or paints. The film is light enough to be held to the roof and walls, at the site, using velcro. Production cost is less than U$10 per tile, and they can be manufactured quicker than any other renewable energy source. A commercial printer would be capable of manufacturing kilometers of the panels each day. Dastoor’s team believes this could be the answer to the country’s search into finding ways to reduce the demand for base-load power.

Image: http://www.npl.co.uk/

It is estimated that there are currently at least 1.2 billion people worldwide without access to electricity, and this technology promises to take it into many remote communities. In addition, it would revolutionize the way in which solar power is provided, in other areas. One of the obstacles currently associated with solar power, is the initial cost of installing the panels. Printed solar tiles can be distributed by energy providers, and packages could be recommended based on each household’s usage requirements. The panels are also ideal for recovery efforts, and disaster relief, because of the speed at which they can be printed and transported via airdrop. They would also be advantageous to military operations, as the panels can provide electricity noiselessly.

The current demonstration site in Australia, has been built as a final testing stage.  Researchers aim to identify any modifications that may be necessary, before the product is marketable. The site sends feedback every half hour, and is the first time the panels have been tested in a real life situation. The long term testing will determine the durability of the printed solar tiles, and has already demonstrated that they have a more constant power flow in low-light and cloud cover, which would prevent customers experiencing dips in their service. The material is also sensitive enough to produce small amounts of energy using moonlight.

Smart Cities – Panasonic Promotes the Future

Most futuristic movies feature cities that have increased functionality, which has been obtained by applying technology to everyday life. Leading technology company, Panasonic, has already begun building these ‘smart cities,’ and have shown where they can be the way forward. Their creation, Fujisawa SSC in Japan, is the world’s first city which incorporates technology into its infrastructure to maximize efficiency. The eco-friendly design was based on five major areas:

Energy – Fujisawa SSC’s energy system was created with the intention of consuming as well as generating energy within the boundaries of the city. 30% of the town’s energy comes from renewable sources, and each household can monitor its consumption online. All lighting fixtures are LED and buildings are equipped with solar panels, storage batteries, fuel celled co-generation units and heat pumped water heaters.

Mobility – The community has a mobility sharing service that encourages residents to share electric cars and bicycles. This reduces traffic in the community, promotes a more active lifestyle and creates convenient ways of travel for each person.

Security – For most people, their family’s safety is of the utmost importance. The town features an integrated security system, which has multiple cameras that are constantly monitored, to keep the environment open with minimal danger.

Healthcare – To promote a healthier environment, top quality healthcare is accessible to all residents of Fujisawa SSC.

Community – Monthly events are organized, which encourage residents to socialize and form a bond with their neighbors. This promotes a closeness in the community, which helps citizens come together to adequately determine what is best for the city’s future development.

Panasonic began as a company that enhanced lifestyles through the application of its products, but have an overall vision of creating a future where ‘smart cities’ dominate on a global scale. Their mission of ‘a better life, a better world’ continues to becomes a reality, as the company entered a partnership with Denver, Colorado to build their second smart city. The project began in 2016, and is expected to take at least ten years to come to fruition.

Aspects of the project that have already been installed include: WiFi, security cameras, sensors that can monitor the environment, and an energy grid with the ability to power the entire city for 72 hours in case of an emergency. More recently, the developers included the Colorado Department of Transportation in the designing and making of the city’s roadways. Road X, which costs approximately $72 million, aims to reduce accidents by facilitating communication between vehicles and the road’s infrastructure. This would include guidance about the best route, as well as an ability to alert drivers that are drifting out of their lanes.

Infrastructure is also being constructed that will connect an autonomous shuttle, from the city, to bus routes on Denver’s Tower Road. Panasonic believes that the city’s completion will result in a global desire for more smart cities. This is just another example of the way in which technology is improving the world, and the company continues to be a leading edge creator in the field.